The UDP-galactose translocator gene is mapped to band Xp11.23-p11.22 containing the Wiskott-Aldrich syndrome locus

@article{Hara1993TheUT,
  title={The UDP-galactose translocator gene is mapped to band Xp11.23-p11.22 containing the Wiskott-Aldrich syndrome locus},
  author={Toshiro Hara and M Yamauchi and Ei-ichi Takahashi and Masanobu Hoshino and Ken-ichi Aoki and Dai Ayusawa and Masao Kawakita},
  journal={Somatic Cell and Molecular Genetics},
  year={1993},
  volume={19},
  pages={571-575}
}
We have cloned a segment of the human gene encoding UDP-galactose translocator by genetic complementation of its defective mutant in mouse FM3A cells. Chromosome mapping using fluorescentin situ hybridization revealed that the cloned gene hybridized to the Xp11.23-11.23 region of the X chromosome. This region is shared by the locus of Wiskott-Aldrich syndrome, an X-linked recessive immunodeficiency disorder, characterized by defective sugar chains on cell surface components. Genetic and… CONTINUE READING