The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies

@inproceedings{Earl2015TheUU,
  title={The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies},
  author={Julie Earl and Daniel Rico and Enrique Carrillo-de-Santa-Pau and Benjam{\'i}n Rodr{\'i}guez-Santiago and Marinela M{\'e}ndez-Pertuz and Herbert Auer and Gonzalo Jes{\'u}s G{\'o}mez and Herbert Barton Grossman and David G. Pisano and Wolfgang A. Schulz and Luis A. P{\'e}rez-Jurado and Alfredo Carrato and Dan Theodorescu and Stephen J. Chanock and Alfonso Valencia and Francisco X Real},
  booktitle={BMC Genomics},
  year={2015}
}
Urothelial bladder cancer is a highly heterogeneous disease. Cancer cell lines are useful tools for its study. This is a comprehensive genomic characterization of 40 urothelial bladder carcinoma (UBC) cell lines including information on origin, mutation status of genes implicated in bladder cancer (FGFR3, PIK3CA, TP53, and RAS), copy number alterations assessed using high density SNP arrays, uniparental disomy (UPD) events, and gene expression. Based on gene mutation patterns and genomic… CONTINUE READING
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