The Type III Secretion Translocation Pore Senses Host Cell Contact.

  title={The Type III Secretion Translocation Pore Senses Host Cell Contact.},
  author={Erin I. Armentrout and Arne Rietsch},
  journal={PLoS pathogens},
  volume={12 3},
Type III secretion systems (T3SS) are nano-syringes used by a wide range of Gram-negative pathogens to promote infection by directly injecting effector proteins into targeted host cells. Translocation of effectors is triggered by host-cell contact and requires assembly of a pore in the host-cell plasma membrane, which consists of two translocator proteins. Our understanding of the translocation pore, how it is assembled in the host cell membrane and its precise role in effector translocation… CONTINUE READING
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