The Type 3 Deiodinase: Epigenetic Control of Brain Thyroid Hormone Action and Neurological Function

@inproceedings{Hernandez2018TheT3,
  title={The Type 3 Deiodinase: Epigenetic Control of Brain Thyroid Hormone Action and Neurological Function},
  author={Arturo Hernandez and J. Patrizia Stohn},
  booktitle={International journal of molecular sciences},
  year={2018}
}
Thyroid hormones (THs) influence multiple processes in the developing and adult central nervous system, and their local availability needs to be maintained at levels that are tailored to the requirements of their biological targets. The local complement of TH transporters, deiodinase enzymes, and receptors is critical to ensure specific levels of TH action in neural cells. The type 3 iodothyronine deiodinase (DIO3) inactivates THs and is highly present in the developing and adult brain, where… CONTINUE READING
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