The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities

@inproceedings{Choi2012TheTP,
  title={The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities},
  author={Mei Yee Choi and Ying Wang and Leo L. Y. Wong and Bing-tai Lu and Wen-yang Chen and Jian-Dong Huang and Julian Alexander Tanner and Rory M Watt},
  booktitle={PloS one},
  year={2012}
}
Inorganic polyphosphate (poly-P), guanosine pentaphosphate (pppGpp) and guanosine tetraphosphate (ppGpp) are ubiquitous in bacteria. These molecules play a variety of important physiological roles associated with stress resistance, persistence, and virulence. In the bacterial pathogen Mycobacterium tuberculosis, the identities of the proteins responsible for the metabolism of polyphosphate and (p)ppGpp remain to be fully established. M. tuberculosis encodes two PPX-GppA homologues, Rv0496 (MTB… CONTINUE READING

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