The Two Cis-Acting Sites, parS1 and oriC1, Contribute to the Longitudinal Organisation of Vibrio cholerae Chromosome I

@inproceedings{David2014TheTC,
  title={The Two Cis-Acting Sites, parS1 and oriC1, Contribute to the Longitudinal Organisation of Vibrio cholerae Chromosome I},
  author={Ariane David and G{\"a}elle Demarre and Leila Muresan and Evelyne Paly and François-Xavier Barre and Christophe Possoz},
  booktitle={PLoS genetics},
  year={2014}
}
The segregation of bacterial chromosomes follows a precise choreography of spatial organisation. It is initiated by the bipolar migration of the sister copies of the replication origin (ori). Most bacterial chromosomes contain a partition system (Par) with parS sites in close proximity to ori that contribute to the active mobilisation of the ori region towards the old pole. This is thought to result in a longitudinal chromosomal arrangement within the cell. In this study, we followed the… CONTINUE READING

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Chromosome segregation in Vibrio cholerae.

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