The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake

Abstract

Trypanosoma cruzi, the etiological agent of Chagas' disease, presents nutritional requirements for several metabolites. It requires heme for the biosynthesis of several heme-proteins involved in essential metabolic pathways like mitochondrial cytochromes and respiratory complexes, as well as enzymes involved in the biosynthesis of sterols and unsaturated… (More)
DOI: 10.1371/journal.pntd.0004359

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