The Trypanosoma cruzi L1Tc and NARTc non-LTR retrotransposons show relative site specificity for insertion.

@article{Bringaud2006TheTC,
  title={The Trypanosoma cruzi L1Tc and NARTc non-LTR retrotransposons show relative site specificity for insertion.},
  author={Fr{\'e}d{\'e}ric Bringaud and Daniella Castanheira Bartholomeu and Ga{\"e}lle Blandin and Arthur L. Delcher and Th{\'e}o Baltz and Najib M El-Sayed and Elodie Ghedin},
  journal={Molecular biology and evolution},
  year={2006},
  volume={23 2},
  pages={411-20}
}
The trypanosomatid protozoan Trypanosoma cruzi contains long autonomous (L1Tc) and short nonautonomous (NARTc) non-long terminal repeat retrotransposons. NARTc (0.25 kb) probably derived from L1Tc (4.9 kb) by 3'-deletion. It has been proposed that their apparent random distribution in the genome is related to the L1Tc-encoded apurinic/apyrimidinic endonuclease (APE) activity, which repairs modified residues. To address this question we used the T. cruzi (CL-Brener strain) genome data to analyze… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…