The Translational Medicine Ontology and Knowledge Base: driving personalized medicine by bridging the gap between bench and bedside

@inproceedings{Luciano2011TheTM,
  title={The Translational Medicine Ontology and Knowledge Base: driving personalized medicine by bridging the gap between bench and bedside},
  author={Joanne S. Luciano and Bo Andersson and Colin R. Batchelor and Olivier Bodenreider and Tim Clark and Christine K. Denney and Christopher Domarew and Thomas Gambet and Lee Harland and Anja Jentzsch and Vipul Kashyap and Peter J. Kos and Julia Kozlovsky and Timothy Lebo and M. Scott Marshall and James P. McCusker and Deborah L. McGuinness and Chimezie Ogbuji and Elgar Pichler and Robert L. Powers and Eric Prud'hommeaux and Matthias Samwald and Lynn M. Schriml and Peter J. Tonellato and Patricia L. Whetzel and Jun Zhao and Susie Stephens and Michel Dumontier},
  booktitle={J. Biomedical Semantics},
  year={2011}
}
BACKGROUND Translational medicine requires the integration of knowledge using heterogeneous data from health care to the life sciences. Here, we describe a collaborative effort to produce a prototype Translational Medicine Knowledge Base (TMKB) capable of answering questions relating to clinical practice and pharmaceutical drug discovery. RESULTS We developed the Translational Medicine Ontology (TMO) as a unifying ontology to integrate chemical, genomic and proteomic data with disease… CONTINUE READING

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