The Toxoplasma gondii rhoptry protein ROP18 is an Irga6‐specific kinase and regulated by the dense granule protein GRA7

@inproceedings{Hermanns2016TheTG,
  title={The Toxoplasma gondii rhoptry protein ROP18 is an Irga6‐specific kinase and regulated by the dense granule protein GRA7},
  author={Thomas Hermanns and Urs Benedikt M{\"u}ller and Stephanie K{\"o}nen‐Waisman and Jonathan Charles Howard and Tobias Steinfeldt},
  booktitle={Cellular microbiology},
  year={2016}
}
In mice, avirulent strains (e.g. types II and III) of the protozoan parasite Toxoplasma gondii are restricted by the immunity-related GTPase (IRG) resistance system. Loading of IRG proteins onto the parasitophorous vacuolar membrane (PVM) is required for vacuolar rupture resulting in parasite clearance. In virulent strain (e.g. type I) infections… CONTINUE READING