The ToxR-mediated organic acid tolerance response of Vibrio cholerae requires OmpU.

@article{Merrell2001TheTO,
  title={The ToxR-mediated organic acid tolerance response of Vibrio cholerae requires OmpU.},
  author={D Scott Merrell and Charles A. Bailey and J. Kaper and Andrew Camilli},
  journal={Journal of bacteriology},
  year={2001},
  volume={183 9},
  pages={2746-54}
}
It was previously demonstrated that the intestinal pathogen Vibrio cholerae could undergo an adaptive stress response known as the acid tolerance response (ATR). The ATR is subdivided into two branches, inorganic ATR and organic ATR. The transcriptional regulator ToxR, while not involved in inorganic ATR, is required for organic ATR in a ToxT-independent manner. Herein, we investigate the effect of organic acid stress on global protein synthesis in V. cholerae and show by two-dimensional gel… CONTINUE READING