The Toll pathway is important for an antiviral response in Drosophila.

  title={The Toll pathway is important for an antiviral response in Drosophila.},
  author={Robert Anthony Zambon and Madhumitha Nandakumar and Vikram N. Vakharia and Louisa P. Wu},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={102 20},
The innate immune response of Drosophila melanogaster is governed by a complex set of signaling pathways that trigger antimicrobial peptide (AMP) production, phagocytosis, melanization, and encapsulation. Although immune responses against both bacteria and fungi have been demonstrated in Drosophila, identification of an antiviral response has yet to be found. To investigate what responses Drosophila mounts against a viral infection, we have developed an in vivo Drosophila X virus (DXV)-based… CONTINUE READING
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