The Tiresias complex: Huntington's disease as a paradigm of testing for late‐onset disorders

@article{Wexler1992TheTC,
  title={The Tiresias complex: Huntington's disease as a paradigm of testing for late‐onset disorders},
  author={Nancy S Wexler},
  journal={The FASEB Journal},
  year={1992},
  volume={6},
  pages={2820 - 2825}
}
  • N. Wexler
  • Published 1 July 1992
  • Medicine
  • The FASEB Journal
Huntington's disease represents the first disorder for which positional cloning techniques successfully localized an autosomal gene — in 1983. Events since that time have proved the gene recalcitrant to identification and characterization. Since 1986, presymptomatic and prenatal testing for Huntington's disease has been available internationally, although on a limited basis. Testing for Huntington's disease provides an excellent model for designing service programs for genetic testing for late… 
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Presymptomatic testing for late‐onset genetic disorders: lessons from Huntington's disease

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  • Medicine
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 1992
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