The Timing of Timezyme Diversification in Vertebrates

  title={The Timing of Timezyme Diversification in Vertebrates},
  author={Damien Cazam{\'e}a-Catalan and Laurence Besseau and Jack Falc{\'o}n and Elodie Magnanou},
  booktitle={PloS one},
All biological functions in vertebrates are synchronized with daily and seasonal changes in the environment by the time keeping hormone melatonin. Its nocturnal surge is primarily due to the rhythmic activity of the arylalkylamine N-acetyl transferase AANAT, which thus became the focus of many investigations regarding its evolution and function. Various vertebrate isoforms have been reported from cartilaginous fish to mammals but their origin has not been clearly established. Using phylogeny… CONTINUE READING
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