The Third Intergroup Rhabdomyosarcoma Study.

@article{Crist1995TheTI,
  title={The Third Intergroup Rhabdomyosarcoma Study.},
  author={WilliamM. Crist and Edmund A. Gehan and Abdelsalam H. Ragab and Paul S. Dickman and Sarah S. Donaldson and Chris L. Fryer and Denman Hammond and Daniel M. Hays and Joerg Herrmann and Rosemarie Heyn},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1995},
  volume={13 3},
  pages={
          610-30
        }
}
PURPOSE The ultimate goal of the Third Intergroup Rhabdomyosarcoma Study (IRS-III, 1984 to 1991) was to improve treatment outcome in children with rhabdomyosarcoma through clinical trials comparing risk-based protocols of surgery and multiagent chemotherapy, with or without irradiation. PATIENTS AND METHODS One thousand sixty-two previously untreated, eligible patients who were entered onto the study after surgery were randomized or assigned to treatment by clinical group (I through IV… CONTINUE READING
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