The Third Domain Ligand Binding Fragment of Alpha-fetoprotein: Detection of Metastasisassociated Molecular Targets

@inproceedings{Mizejewski2017TheTD,
  title={The Third Domain Ligand Binding Fragment of Alpha-fetoprotein: Detection of Metastasisassociated Molecular Targets},
  author={Gerald J. Mizejewski},
  year={2017}
}
Human alpha-fetoprotein (AFP) was one of the first biomarkers developed as a cancer biomarker and is still today considered the “gold standard” biomarker for liver cancer. AFP is a glycopolypeptide exhibiting a molecular mass of 69 kD with a 3-5% carbohydrate content [1]. Structurally, the full-length AFP molecule consists of three domains forming nine layers of peptide loops configured by 15 cysteine disulfide bridges [2]. The twodimensional (secondary) image of AFP has been determined and… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 81 REFERENCES

ADAM9 expression promotes an aggressive lung adenocarcinoma phenotype.

  • Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  • 2017
VIEW 1 EXCERPT

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