The Therapeutic Misconception at 25: Treatment, Research, and Confusion

@article{Kimmelman2007TheTM,
  title={The Therapeutic Misconception at 25: Treatment, Research, and Confusion},
  author={Jonathan Kimmelman},
  journal={Hastings Center Report},
  year={2007},
  volume={37},
  pages={36 - 42}
}
  • J. Kimmelman
  • Published 12 November 2007
  • Psychology
  • Hastings Center Report
"Therapeutic misconception" has been misconstrued, and some of the newer, mistaken interpretations are troublesome. They exaggerate the distinction between research and treatment, revealing problems in the foundations of research ethics and possibly weakening informed consent. 
An approach to evaluating the therapeutic misconception.
TLDR
A report proposes a defi nition that does not refer to anything "therapeutic" and says that the therapeutic misconcep tion occurs when individuals fail to understand that they are under a therapeutic misconception.
Eschewing definitions of the therapeutic misconception: a family resemblance analysis.
  • D. Goldberg
  • Psychology
    The Journal of medicine and philosophy
  • 2011
TLDR
The paper addresses the social and cultural factors that seem to animate the TM among subjects and adopts a Wittgensteinian approach to evaluating the TM, suggesting that interlocutors do not need any analytic definition of the TM to use the term meaningfully in thinking about the moral implications of theTM in practice.
Presuming Patient Autonomy in the Face of Therapeutic Misconception
TLDR
This article argues that the mere expression of aspects of therapeutic misconception should not necessarily displace the presumption of subject autonomy or undermine ethical inclusion in research for at least three reasons.
Reassessing the measurement and presence of therapeutic misconception in a phase 1 setting
TLDR
A lower TM estimate in the phase 1 setting than previously found in a similar cohort is reported, threatening valid informed consent to participate in clinical trials.
Therapeutic misconceptions and misestimations in oncology: a clinical trial nurse's guide.
  • Jennifer Scott
  • Medicine, Psychology
    Clinical journal of oncology nursing
  • 2013
TLDR
This article will define therapeutic misconceptions and misestimations, explore contributing factors, and explain how they can be prevented by clinical trial nurses.
Why is therapeutic misconception so prevalent?
TLDR
It is suggested that reducing TM requires encouraging subjects to adjust their frame, not just add information to their existing frame, and what is necessary is a scientific reframing of participation in a clinical trial.
Beyond the ‘therapeutic misconception’: Research, care and moral friction
TLDR
It is argued that the objectives of health care and research often merge in mutually constitutive practices and the presentation of the research-care tension as an ethical dilemma is misleading and even part of the problem that must be dealt with by those involved.
Clinical research in context: reexamining the distinction between research and practice.
TLDR
This analysis shows that, from an epistemological point of view, clinical research and clinical practice are not sharply distinct but intimately intertwined, which has profound implications for the ethics of human subjects research.
The “Research Misconception” and the SUPPORT Trial: Toward Evidence-Based Consensus
TLDR
In the SUPPORT trial and similar CER or standard of care research, the focus must not focus on the disclosure of risks to an extent that other requirements of respect for persons are ignored.
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