The Therapeutic Effects of Optimal Dose of Mesenchymal Stem Cells in a Murine Model of an Elastase Induced-Emphysema

@inproceedings{Kim2015TheTE,
  title={The Therapeutic Effects of Optimal Dose of Mesenchymal Stem Cells in a Murine Model of an Elastase Induced-Emphysema},
  author={You-sun Kim and Ji-young Kim and Jin Won Huh and Sei Won Lee and Soo Jin Choi and Yeon Mok Oh},
  booktitle={Tuberculosis and respiratory diseases},
  year={2015}
}
BACKGROUND Chronic obstructive pulmonary disease is characterized by emphysema, chronic bronchitis, and small airway remodeling. The alveolar destruction associated with emphysema cannot be repaired by current clinical practices. Stem cell therapy has been successfully used in animal models of cigarette smoke- and elastase-induced emphysema. However, the optimal dose of mesenchymal stem cells (MSCs) for the most effective therapy has not yet been determined. It is vital to determine the optimal… CONTINUE READING