The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice

@article{Zheng2015TheTE,
  title={The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice},
  author={Jian Zheng and Wai-lan Wu and Yinping Liu and Zheng Xiang and Ming Liu and Kwok-Hung Chan and Siu-ying Lau and Kwok-Tai Lam and Kelvin Kai-Wang To and Jasper Fuk-Woo Chan and Lanjuan Li and Honglin Chen and Yu-Lung Lau and Kwok Yung Yuen and Wenwei Tu},
  journal={PLoS ONE},
  year={2015},
  volume={10}
}
A novel avian influenza virus H7N9 infection occurred among human populations since 2013. Although the lack of sustained human-to-human transmission limited the epidemics caused by H7N9, the late presentation of most patients and the emergence of neuraminidase-resistant strains made the development of novel antiviral strategy against H7N9 in urgent demands. In this study, we evaluated the potential of pamidronate, a pharmacological phosphoantigen that can specifically boost human Vδ2-T-cell, on… 
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