The Temporal Relationship Between Symptom Change and Treatment Discontinuation in a Pooled Analysis of 4 Schizophrenia Trials

@article{Kinon2008TheTR,
  title={The Temporal Relationship Between Symptom Change and Treatment Discontinuation in a Pooled Analysis of 4 Schizophrenia Trials},
  author={B. Kinon and H. Ascher-Svanum and D. Adams and L. Chen},
  journal={Journal of Clinical Psychopharmacology},
  year={2008},
  volume={28},
  pages={544-549}
}
Treatment discontinuation is common in antipsychotic trials for the treatment of schizophrenia and is often associated with symptom worsening. This study assessed the timing and the magnitude of symptom change associated with treatment discontinuation for any cause, and whether improvement in specific symptom domains was predictive of treatment persistence. This post hoc analysis used pooled data from 1627 patients with schizophrenia spectrum disorders who were enrolled in 4 randomized, double… Expand
Predictors of switching antipsychotic medications in the treatment of schizophrenia
Impact of symptom resolution on medication adherence in first episode psychosis
Clinical predictors of therapeutic response to antipsychotics in schizophrenia
...
1
2
...

References

SHOWING 1-10 OF 40 REFERENCES
The association of dropout and outcome in trials of antipsychotic medication and its implications for dealing with missing data.
Early prediction of antipsychotic response in schizophrenia.
Determinants of medication compliance in schizophrenia: empirical and clinical findings.
...
1
2
3
4
...