The Temporal Expression Pattern of Alpha-Synuclein Modulates Olfactory Neurogenesis in Transgenic Mice

@inproceedings{Schreglmann2015TheTE,
  title={The Temporal Expression Pattern of Alpha-Synuclein Modulates Olfactory Neurogenesis in Transgenic Mice},
  author={Sebastian R Schreglmann and Martin Regensburger and Edward M. Rockenstein and Eliezer Masliah and Wei Xiang and J{\"u}rgen Winkler and Beate Winner},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND Adult neurogenesis mirrors the brain´s endogenous capacity to generate new neurons throughout life. In the subventricular zone/ olfactory bulb system adult neurogenesis is linked to physiological olfactory function and has been shown to be impaired in murine models of neuronal alpha-Synuclein overexpression. We analyzed the degree and temporo… CONTINUE READING