The Tem1 small GTPase controls actomyosin and septin dynamics during cytokinesis.

@article{Lippincott2001TheTS,
  title={The Tem1 small GTPase controls actomyosin and septin dynamics during cytokinesis.},
  author={John Lippincott and Katie B. Shannon and Wenying Shou and Raymond J Deshaies and Ruixin Li},
  journal={Journal of cell science},
  year={2001},
  volume={114 Pt 7},
  pages={1379-86}
}
Cytokinesis in budding yeast involves an actomyosin-based ring which assembles in a multistepped fashion during the cell cycle and constricts during cytokinesis. In this report, we have investigated the structural and regulatory events that occur at the onset of cytokinesis. The septins, which form an hour-glass like structure during early stages of the cell cycle, undergo dynamic rearrangements prior to cell division: the hourglass structure splits into two separate rings. The contractile ring… CONTINUE READING
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