The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.

@article{Kurreeman2010TheTR,
  title={The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.},
  author={Fina A. S. Kurreeman and George N. Goulielmos and Behrooz Z. Alizadeh and B. Bryan Rueda and Jeanine J. Houwing-Duistermaat and Elena C S{\'a}nchez and Marianna R. Bevova and Timothy R. D. J. Radstake and Madelon C. Vonk and Emmanouil Galanakis and Norberto Ortego and Willem Verduyn and Maria I. Zervou and Bart O Roep and B{\'a}rbara Dema and Laura Espino and Elena Urcelay and Dimitrios T. Boumpas and Leonard H van den Berg and Cisca Wijmenga and Bobby P. C. Koeleman and Tom W. J. Huizinga and Ren{\'e} E M Toes and Javier Mart{\'i}n},
  journal={Annals of the rheumatic diseases},
  year={2010},
  volume={69 4},
  pages={696-9}
}
OBJECTIVES The TRAF1-C5 locus has recently been identified as a genetic risk factor for rheumatoid arthritis (RA). Since genetic risk factors tend to overlap with several autoimmune diseases, a study was undertaken to investigate whether this region is associated with type 1 diabetes (TID), celiac disease (CD), systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). METHODS The most consistently associated SNP, rs10818488, was genotyped in a total of 735 patients with T1D, 1049 with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…