The TLR and IL-1 signalling network at a glance.

Abstract

Toll-like receptors (TLRs) and the receptors for interleukin (IL)-1, IL-18 and IL-33 are required for defence against microbial pathogens but, if hyper-activated or not switched off efficiently, can cause tissue damage and inflammatory and autoimmune diseases. Understanding how the checks and balances in the system are integrated to fight infection without… (More)
DOI: 10.1242/jcs.149831

Topics

Cite this paper

@article{Cohen2014TheTA, title={The TLR and IL-1 signalling network at a glance.}, author={Philip Cohen}, journal={Journal of cell science}, year={2014}, volume={127 Pt 11}, pages={2383-90} }