The TIGRFAMs database of protein families

  title={The TIGRFAMs database of protein families},
  author={Daniel H. Haft and Jeremy D. Selengut and Owen White},
  journal={Nucleic acids research},
  volume={31 1},
TIGRFAMs is a collection of manually curated protein families consisting of hidden Markov models (HMMs), multiple sequence alignments, commentary, Gene Ontology (GO) assignments, literature references and pointers to related TIGRFAMs, Pfam and InterPro models. These models are designed to support both automated and manually curated annotation of genomes. TIGRFAMs contains models of full-length proteins and shorter regions at the levels of superfamilies, subfamilies and equivalogs, where… 

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