The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription.

@article{Bosch2006TheTD,
  title={The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription.},
  author={John R ten Bosch and Joseph A. Benavides and Thomas W. Cline},
  journal={Development},
  year={2006},
  volume={133 10},
  pages={1967-77}
}
The Drosophila sex-determination switch gene Sex-lethal (Sxl) and the X-chromosome signal element genes (XSEs) that induce the female-specific expression of Sxl are transcribed extremely early in development when most of the genome of this organism is still silent. The DNA sequence CAGGTAG had been implicated in this pre-cellular blastoderm activation of sex-determination genes. A genome-wide computational search, reported here, suggested that CAGGTAG is not specific to early sex-determination… CONTINUE READING