The T4 phage UvsW protein contains both DNA unwinding and strand annealing activities.

@article{Nelson2007TheTP,
  title={The T4 phage UvsW protein contains both DNA unwinding and strand annealing activities.},
  author={Scott W. Nelson and Stephen J Benkovic},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 1},
  pages={407-16}
}
UvsW protein belongs to the SF2 helicase family and is one of three helicases found in T4 phage. UvsW governs the transition from origin-dependent to origin-independent replication through the dissociation of R-loops located at the T4 origins of replication. Additionally, in vivo evidence indicates that UvsW plays a role in recombination-dependent replication and/or DNA repair. Here, the biochemical properties of UvsW helicase are described. UvsW is a 3' to 5' helicase that unwinds a wide… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.

Dual Activities of T4 UvsW Helicase 416 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

  • G. Ira, A. Malkova, G. Liberi, M. Foiani, J. E. andHaber
  • J. Biol. Chem. 10.1074/jbc.M608153200
  • 2003

Similar Papers

Loading similar papers…