The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy

@inproceedings{PastorIdoate2013TheTM,
  title={The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy},
  author={Salvador Pastor-Idoate and Irene Rodr{\'i}guez-Hern{\'a}ndez and Jimena Rojas and I Rodrigo Fern{\'a}ndez and Mar{\'i}a Teresa Garc{\'i}a-Guti{\'e}rrez and Jos{\'e} Mar{\'i}a Ruiz-Moreno and A Rocha-Sousa and Yashin Ramkissoon and Steven E Harsum and Robert E Maclaren and David Charteris and Jan C. VanMeurs and Rogelio Gonz{\'a}lez-Sarmiento and J Carlos Pastor},
  booktitle={PloS one},
  year={2013}
}
Proliferative vitreoretinopathy (PVR) is still the major cause of failure in retinal detachment (RD) surgery. It is believed that down-regulation in the p53 pathway could be an important key in PVR pathogenesis. The purpose was to evaluate the impact of T309G MDM2 polymorphism (rs2279744) in PVR. Distribution of T309G MDM2 genotypes among European subjects… CONTINUE READING