The Synergy Between Stem Cell Factor (SCF) and Granulocyte Colony-stimulating Factor (G-CSF): Molecular Basis and Clinical Relevance

@article{Duarte2002TheSB,
  title={The Synergy Between Stem Cell Factor (SCF) and Granulocyte Colony-stimulating Factor (G-CSF): Molecular Basis and Clinical Relevance},
  author={R. Duarte and D. Frank},
  journal={Leukemia & Lymphoma},
  year={2002},
  volume={43},
  pages={1179 - 1187}
}
Stem cell factor (SCF), an essential growth factor in normal hematopoiesis, exerts potent effects when combined with cytokines. In particular, its synergy with granulocyte colony-stimulating factor (G-CSF) results in important biologic responses. These include enhancement of ex vivo long-term expansion of human primitive hematopoietic cells and increased mobilization of peripheral blood progenitor cells (PBPC) for transplantation. Despite the clinical importance of the interaction between SCF… Expand
52 Citations
Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines
The Effects of Hematopoietic Growth Factors on Neurite Outgrowth
Experimental culture conditions are critical for ex vivo expansion of hematopoietic cells.
  • L. Douay
  • Biology, Medicine
  • Journal of hematotherapy & stem cell research
  • 2001
Effects of autologous bone marrow-derived stem cell mobilization on acute tubular necrosis and cell apoptosis in rats.
Granulocyte-colony stimulating factor: a new player for the enteric nervous system
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 114 REFERENCES
SCF and G-CSF lead to the synergistic induction of proliferation and gene expression through complementary signaling pathways.
...
1
2
3
4
5
...