The Suramin Analog 4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic Acid (NF110) Potently Blocks P2X3 Receptors: Subtype Selectivity Is Determined by Location of Sulfonic Acid Groups

@article{Hausmann2006TheSA,
  title={The Suramin Analog 4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic Acid (NF110) Potently Blocks P2X3 Receptors: Subtype Selectivity Is Determined by Location of Sulfonic Acid Groups},
  author={Ralf Hausmann and J{\"u}rgen Rettinger and Zoltan Gerevich and Sabine Meis and Matthias U. Kassack and Peter Ill{\'e}s and G{\"u}nter Lambrecht and Günther Schmalzing},
  journal={Molecular Pharmacology},
  year={2006},
  volume={69},
  pages={2058 - 2067}
}
We have previously identified the suramin analog 4,4′,4″,4″′-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid (NF449) as a low nanomolar potency antagonist of recombinant P2X1 receptors. Here, we characterize, by two-electrode voltage-clamp electrophysiology, three isomeric suramin analogs designated para-4,4′,4″,4″″-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetrakis-benzenesulfonic acid (NF110), meta-(3,3′,3″,3″″-(carbonylbis(imino-5… 
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The novel ferroceneophane 1c, is the product of the reaction of silicon tetrachloride with the dilithio derivative of N,N-dimethyl-α-ferrocenylethylamine. Crystals of 1c are monoclinic, space group…
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