The Suppressive Role and Aberrent Promoter Methylation of BTG3 in the Progression of Hepatocellular Carcinoma

@inproceedings{Lv2013TheSR,
  title={The Suppressive Role and Aberrent Promoter Methylation of BTG3 in the Progression of Hepatocellular Carcinoma},
  author={Zhenbing Lv and Huichun Zou and Kaiwen Peng and Jianmei Wang and Yi Ding and Yuling Li and Xiaoli Ren and Feifei Wang and Rui Chang and Li Liang and Yanqing Ding},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND BTG3 (B-cell translocation gene 3) has been identified as a tumor suppressor and hypermethylation contributes to its down-regulation in some tumors, but its role in hepatocellular carcinoma (HCC) remain unknown. This study aimed to detect the expression and methylation status of BTG3 in HCC cell lines or tissues, and determine its function in HCC progression. METHODOLOGY The expression of BTG3 was detected in HCC cell lines and HCC tissue by real-time RT-PCR, Western blot or… CONTINUE READING

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