The Subventricular Zone En-face: Wholemount Staining and Ependymal Flow

@inproceedings{Mirzadeh2010TheSZ,
  title={The Subventricular Zone En-face: Wholemount Staining and Ependymal Flow},
  author={Zaman Mirzadeh and Fiona Doetsch and Kazunobu Sawamoto and Hynek Wichterle and Arturo Alvarez-Buylla},
  booktitle={Journal of visualized experiments : JoVE},
  year={2010}
}
The walls of the lateral ventricles contain the largest germinal region in the adult mammalian brain. The subventricular zone (SVZ) in these walls is an extensively studied model system for understanding the behavior of neural stem cells and the regulation of adult neurogenesis. Traditionally, these studies have relied on classical sectioning techniques for histological analysis. Here we present an alternative approach, the wholemount technique, which provides a comprehensive, en-face view of… CONTINUE READING
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