The Subcellular Localization of Dopamine and Acetylcholine in the Dog Caudate Nucleus.

@article{Laverty1963TheSL,
  title={The Subcellular Localization of Dopamine and Acetylcholine in the Dog Caudate Nucleus.},
  author={Richard Laverty and I. Arthur Michaelson and Dana Sharman and Victor P. Whittaker},
  journal={British journal of pharmacology and chemotherapy},
  year={1963},
  volume={21},
  pages={482-90}
}
The distribution of dopamine (3,4-dihydroxyphenylethylamine) between the subcellular fractions from homogenates of dog caudate nucleus was compared with the distributions of acetylcholine, 5-hydroxytryptamine and lactate dehydrogenase activity. The distributions of noradrenaline and 5-hydroxytryptamine between the subcellular fractions from homogenates of dog hypothalamus were also determined. Most of the dopamine, in contrast to acetylcholine, occurred in the soluble supernatant fraction; the… CONTINUE READING

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