The Structure and Interactions of SpoIISA and SpoIISB, a Toxin-Antitoxin System in Bacillus subtilis*

@inproceedings{Florek2011TheSA,
  title={The Structure and Interactions of SpoIISA and SpoIISB, a Toxin-Antitoxin System in Bacillus subtilis*},
  author={Patrik Florek and Vladimir M. Levdikov and Elena V. Blagova and Andrey Lebedev and Rostislav {\vS}krabana and Stanislava Re{\vs}et{\'a}rov{\'a} and Pamela Pavel{\vc}{\'i}kov{\'a} and Imrich Bar{\'a}k and Anthony James Wilkinson},
  booktitle={The Journal of biological chemistry},
  year={2011}
}
Spore formation in Bacillus subtilis begins with an asymmetric cell division, following which differential gene expression is established by alternative compartment-specific RNA polymerase σ factors. The spoIISAB operon of B. subtilis was identified as a locus whose mutation leads to increased activity of the first sporulation-specific sigma factor, σ(F). Inappropriate spoIISA expression causes lysis of vegetatively growing B. subtilis cells and Escherichia coli cells when expressed… CONTINUE READING