The Structure and Function of the Na,K-ATPase Isoforms in Health and Disease

@inproceedings{Clausen2017TheSA,
  title={The Structure and Function of the Na,K-ATPase Isoforms in Health and Disease},
  author={Michael Voldsgaard Clausen and Florian Hilbers and Hanne Poulsen},
  booktitle={Front. Physiol.},
  year={2017}
}
The sodium and potassium gradients across the plasma membrane are used by animal cells for numerous processes, and the range of demands requires that the responsible ion pump, the Na,K-ATPase, can be fine-tuned to the different cellular needs. Therefore, several isoforms are expressed of each of the three subunits that make a Na,K-ATPase, the alpha, beta and FXYD subunits. This review summarizes the various roles and expression patterns of the Na,K-ATPase subunit isoforms and maps the sequence… CONTINUE READING

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