The Stimulus Selectivity and Connectivity of Layer Six Principal Cells Reveals Cortical Microcircuits Underlying Visual Processing

@article{VlezFort2014TheSS,
  title={The Stimulus Selectivity and Connectivity of Layer Six Principal Cells Reveals Cortical Microcircuits Underlying Visual Processing},
  author={Mateo V{\'e}lez-Fort and Charly V. Rousseau and Christian J. Niedworok and Ian R Wickersham and Ede A Rancz and Alexander P.Y. Brown and Molly Strom and Troy W. Margrie},
  journal={Neuron},
  year={2014},
  volume={83},
  pages={1431-1443}
}
Sensory computations performed in the neocortex involve layer six (L6) cortico-cortical (CC) and cortico-thalamic (CT) signaling pathways. Developing an understanding of the physiological role of these circuits requires dissection of the functional specificity and connectivity of the underlying individual projection neurons. By combining whole-cell recording from identified L6 principal cells in the mouse primary visual cortex (V1) with modified rabies virus-based input mapping, we have… CONTINUE READING

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