The Staphylococcus aureus KdpDE two-component system couples extracellular K+ sensing and Agr signaling to infection programming.

@article{Xue2011TheSA,
  title={The Staphylococcus aureus KdpDE two-component system couples extracellular K+ sensing and Agr signaling to infection programming.},
  author={Ting Xue and Yibo You and De Yuan Hong and Haipeng Sun and Baolin Sun},
  journal={Infection and immunity},
  year={2011},
  volume={79 6},
  pages={2154-67}
}
The Kdp system is widely distributed among bacteria. In Escherichia coli, the Kdp-ATPase is a high-affinity K+ uptake system and its expression is activated by the KdpDE two-component system in response to K+ limitation or salt stress. However, information about the role of this system in many bacteria still remains obscure. Here we demonstrate that KdpFABC in Staphylococcus aureus is not a major K+ transporter and that the main function of KdpDE is not associated with K+ transport but that… CONTINUE READING

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