The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane.

Abstract

HIV type 1 (HIV-1) assembly and egress are driven by the viral protein Gag and occur at the plasma membrane in T cells. Recent evidence indicates that secretory vesicles and machinery are essential components of virus packaging in both T cells and macrophages. However, the pathways and cellular mediators of Gag targeting to the plasma membrane are not well… (More)

Topics

8 Figures and Tables

Slides referencing similar topics