The Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation.

Abstract

The Src family kinases (SFKs) play essential roles in collagen- and von Willebrand factor (VWF)-mediated platelet activation. However, the roles of SFKs in G protein-coupled receptor-mediated platelet activation and the molecular mechanisms whereby SFKs are activated by G protein-coupled receptor stimulation are not fully understood. Here we show that the… (More)
DOI: 10.1074/jbc.M112.393124

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Cite this paper

@article{Xiang2012TheSF, title={The Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation.}, author={Binggang Xiang and Guoying Zhang and Lucia Stefanini and Wolfgang Bergmeier and Theodore Kent Gartner and Sidney W Whiteheart and Zhenyu Li}, journal={The Journal of biological chemistry}, year={2012}, volume={287 49}, pages={41277-87} }