The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.

@article{Mazzi2015TheSK,
  title={The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.},
  author={Paola Mazzi and Elena Caveggion and Jos{\`e} A Lapinet-Vera and Clifford A Lowell and Giorgio Berton},
  journal={Journal of immunology},
  year={2015},
  volume={195 5},
  pages={2383-95}
}
Myeloid leukocyte recruitment into the lung in response to environmental cues represents a key factor for the induction of lung damage. We report that Hck- and Fgr-deficient mice show a profound impairment in early recruitment of neutrophils and monocytes in response to bacterial LPS. The reduction in interstitial and airway neutrophil recruitment was not… CONTINUE READING