The Spir actin organizers are involved in vesicle transport processes

@article{Kerkhoff2001TheSA,
  title={The Spir actin organizers are involved in vesicle transport processes},
  author={Eugen Kerkhoff and Jeremy C Simpson and Cornelia B. Leberfinger and Ines M. Otto and Tobias Doerks and Peer Bork and Ulf R{\"u}diger Rapp and Thomas Raabe and Rainer Pepperkok},
  journal={Current Biology},
  year={2001},
  volume={11},
  pages={1963-1968}
}
The p150-Spir protein, which was discovered as a phosphorylation target of the Jun N-terminal kinase, is an essential regulator of the polarization of the Drosophila oocyte. Spir proteins are highly conserved between species and belong to the family of Wiskott-Aldrich homology region 2 (WH2) proteins involved in actin organization. The C-terminal region of Spir encodes a zinc finger structure highly homologous to FYVE motifs. A region with high homology between the Spir family proteins is… CONTINUE READING
35 Citations
21 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 21 references

The patterning of the Drosophila oocyte

  • IM Otto, T Raabe, UE Rennefahrt, P Bork, UR Rapp, E Kerkhoff
  • Development
  • 1996
Highly Influential
7 Excerpts

Phosphatidylinositol 4 , 5bisphosphate meinschaft ( KE 447 / 3 - 1 , SFB 465 ) . induces actinbased movement of raftenriched vesicles through WASPArp 2 / 3

  • AL Rozelle, LM Machesky, M Yamamoto, MH Driessens, RH Insall, MG Roth
  • Curr Biol
  • 2000

Similar Papers

Loading similar papers…