The Spike-Timing Dependence of Plasticity

@article{Feldman2012TheSD,
  title={The Spike-Timing Dependence of Plasticity},
  author={Daniel E Feldman},
  journal={Neuron},
  year={2012},
  volume={75},
  pages={556-571}
}
In spike-timing-dependent plasticity (STDP), the order and precise temporal interval between presynaptic and postsynaptic spikes determine the sign and magnitude of long-term potentiation (LTP) or depression (LTD). STDP is widely utilized in models of circuit-level plasticity, development, and learning. However, spike timing is just one of several factors (including firing rate, synaptic cooperativity, and depolarization) that govern plasticity induction, and its relative importance varies… CONTINUE READING
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