The Spermicidal Powers of Chemical Contraceptives. VI. An Improved Test for Suppositories

@article{Baker1934TheSP,
  title={The Spermicidal Powers of Chemical Contraceptives. VI. An Improved Test for Suppositories},
  author={JOHN R. Baker and R. M. Ranson},
  journal={Epidemiology and Infection},
  year={1934},
  volume={34},
  pages={474 - 485}
}
1. A fluid is described in which cavy sperms react to the most diverse substances almost exactly as do human sperms in human semen. This fluid, called albumen-saline, consists of: 0·9% sodium chloride solution … 0·7 c.c. Egg-white … … … … 2·3 c.c. 2. A detailed description is given of a new technique for comparing the spermicidal powers and rate of disintegration of suppositories (including foam tablets). 3. The new test differs from the old chiefly in allowing only five minutes for the… 
4 Citations

Sex in the laboratory: the Family Planning Association and contraceptive science in Britain, 1929–1959

  • Natasha Szuhan
  • Medicine
    The British Journal for the History of Science
  • 2018
TLDR
In Britain contraceptive standards were imagined and implemented at least two decades earlier by the Family Planning Association, which sought to legitimize contraceptive methods, practice and provision through the foundation of the field of contraceptive science.

A study of suppository bases. II. A colorimetric method for measuring medicinal release from suppository bases.

  • H. GrossC. Becker
  • Biology
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association
  • 1953
TLDR
The colorimetric method developed and used in this investigation serves as one standard for determining the relative value of a suppository base in regard to the release of its active medicament, but is limited to an in vitro study.

A study of suppository bases. I. Review of literature.

  • H. GrossC. Becker
  • Computer Science
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association
  • 1953
TLDR
A review of the literature on suppository bases shows that much work has been done on fattype bases such as cocoa butter, but there seems to be little or no work done with such compounds as plastics, synthetic resins, and other similar condensation products.

The drug release characteristics of various rectal suppositories as determined by specific ion electrodes

Suppositories containing sodium phenobarbitone (200 mg) were manufactured with the following bases; cocoa butter, cocoa butter plus beeswax, Dehydag and polyethylene glycols. The release of sodium

References

SHOWING 1-3 OF 3 REFERENCES

The Spermicidal Powers of Chemical Contraceptives: II. Pure Substances

1. A technique for comparing the spermicidal powers of pure substances is described in detail. It is hoped that this may be accepted as the standard technique for the purpose. 2. The killing

The Spermicidal Powers of Chemical Contraceptives: III. Pessaries

TLDR
Semori is the most spermicidal pessary of the nine investigated, and Speton relies for its sPermicidal power wholly upon its foam-producing substances.

The Spermicidal Powers of Chemical Contraceptives. V. A Comparison of Human Sperms with those of the Guinea-Pig

  • J. Baker
  • Biology, Chemistry
    Epidemiology and Infection
  • 1932
TLDR
There exists a substance in human semen which protects both human and guinea-pig sperms against certain chemicals, especially sodium oleate, orthovanillin and potassium borotartrate.