The Sp185/333 immune response genes and proteins are expressed in cells dispersed within all major organs of the adult purple sea urchin.

@article{Majeske2013TheSI,
  title={The Sp185/333 immune response genes and proteins are expressed in cells dispersed within all major organs of the adult purple sea urchin.},
  author={Audrey J. Majeske and Taras K Oleksyk and L Courtney Smith},
  journal={Innate immunity},
  year={2013},
  volume={19 6},
  pages={569-87}
}
Purple sea urchins (Strongylocentrotus purpuratus) express a highly variable set of immune genes called Sp185/333 by two subtypes of coelomocytes: the polygonal and small phagocytes. We report that the Sp185/333 genes and their encoded proteins are also expressed in all of the major organs in the adult sea urchin, including the axial organ, pharynx, esophagus, intestine and gonads. After immune challenge, there is an increase in the level of Sp185/333 mRNA in cells associated with the intestine… CONTINUE READING
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