The Significance of Notch1 Compared with Notch3 in High Metastasis and Poor Overall Survival in Hepatocellular Carcinoma

@inproceedings{Zhou2013TheSO,
  title={The Significance of Notch1 Compared with Notch3 in High Metastasis and Poor Overall Survival in Hepatocellular Carcinoma},
  author={Liang Zhou and Ning Zhang and Wenjie Song and Nan You and Qingjun Li and Wei Sun and Yong Zhang and Desheng Wang and Kefeng Dou},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND The prognosis for patients with hepatocellular carcinoma (HCC) is poor, and the mechanisms underlying the development of HCC remain unclear. Notch1 and Notch3 may be involved in malignant transformation, although their roles remain unknown. MATERIALS AND METHODS HCC tissues were stained with anti-Notch1 or -Notch3 antibody. The migration and invasion capacities of the cells were measured with transwell cell culture chambers. RT-PCR was used to measure the expression of Notch1 and… CONTINUE READING
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