The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells.

@article{Warner2000TheSA,
  title={The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells.},
  author={A J Warner and Jennifer Lopez-Dee and Emma Knight and James R. Feramisco and Sally A. Prigent},
  journal={The Biochemical journal},
  year={2000},
  volume={347 Pt 2},
  pages={
          501-9
        }
}
Despite much progress in recent years, the precise signalling events triggered by the vascular-endothelial-growth-factor (VEGF) receptors, fms-like tyrosine kinase (Flt1) and kinase insert domain-containing receptor (KDR), are incompletely defined. Results obtained when Flt1 and KDR are individually expressed in fibroblasts or porcine aortic endothelial cells have not been entirely consistent with those observed in other endothelial cells expressing both receptors endogenously. It has also been… CONTINUE READING

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