The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size

@inproceedings{Rideout2015TheSD,
  title={The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size},
  author={Elizabeth J. Rideout and Marcus S. Narsaiya and Savraj S Grewal and Artyom Kopp},
  booktitle={PLoS genetics},
  year={2015}
}
Almost all animals show sex differences in body size. For example, in Drosophila, females are larger than males. Although Drosophila is widely used as a model to study growth, the mechanisms underlying this male-female difference in size remain unclear. Here, we describe a novel role for the sex determination gene transformer (tra) in promoting female body growth. Normally, Tra is expressed only in females. We find that loss of Tra in female larvae decreases body size, while ectopic Tra… CONTINUE READING
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