The Sequence of the Human Genome

  title={The Sequence of the Human Genome},
  author={J. Venter and M. Adams and E. W. Myers and P. Li and R. Mural and G. Sutton and H. Smith and M. Yandell and C. Evans and R. Holt and J. Gocayne and P. Amanatides and R. Ballew and D. Huson and J. Wortman and Q. Zhang and C. Kodira and X. H. Zheng and L. Chen and M. Skupski and G. Subramanian and P. Thomas and J. Zhang and George L. Gabor Miklos and C. Nelson and Samuel Broder and A. Clark and J. Nadeau and V. A. Mckusick and N. Zinder and A. Levine and R. Roberts and M. Simon and C. Slayman and Michael W. Hunkapiller and R. Bolanos and A. Delcher and Ian M. Dew and Daniel P. Fasulo and M. Flanigan and L. Florea and A. Halpern and Sridhar Hannenhalli and S. Kravitz and S. L{\'e}vy and C. Mobarry and K. Reinert and K. Remington and J. Abu-Threideh and E. Beasley and Kendra Biddick and V. Bonazzi and R. C. Brandon and M. Cargill and Ishwar Chandramouliswaran and R. Charlab and Kabir Chaturvedi and Z. Deng and V. D. Francesco and P. Dunn and K. Eilbeck and C. Evangelista and A. Gabrielian and W. Gan and Wangmao Ge and F. Gong and Z. Gu and P. Guan and T. J. Heiman and M. Higgins and R. Ji and Z. Ke and K. A. Ketchum and Z. Lai and Y. Lei and Z. Li and J. Li and Y. Liang and X. Lin and Fu Lu and G. Merkulov and N. Milshina and H. M. Moore and A. K. Naik and V. A. Narayan and B. Neelam and D. Nusskern and D. Rusch and S. Salzberg and W. Shao and B. Shue and Jingtao Sun and Z. Wang and A. Wang and X. Wang and J. Wang and Ming-Hui Wei and R. Wides and C. Xiao and C. Yan and A. Yao and J. Ye and M. Zhan and W. Zhang and Hongyu Zhang and Q. Zhao and L. Zheng and F. Zhong and W. Zhong and S. C. Zhu and S. Zhao and D. Gilbert and Suzanna Baumhueter and Gene Spier and C. Carter and A. Cravchik and T. Woodage and F. Ali and Huijin An and Aderonke Awe and D. Baldwin and H. Baden and M. Barnstead and Ian Barrow and K. Beeson and D. Busam and A. Carver and A. Center and M. Cheng and Liz Curry and Steve Danaher and L. Davenport and R. Desilets and S. Dietz and K. Dodson and L. Doup and S. Ferriera and N. Garg and Andres Gluecksmann and B. Hart and J. Haynes and C. Haynes and C. Heiner and S. Hladun and D. Hostin and Jarrett T. Houck and T. Howland and C. Ibegwam and J. Johnson and F. Kalush and L. Kline and S. Koduru and Amy Love and Felecia Mann and D. May and Steven McCawley and T. McIntosh and I. McMullen and Mee C. Moy and L. Moy and B. Murphy and K. Nelson and Cynthia M Pfannkoch and Eric C. Pratts and V. Puri and H. Qureshi and M. Reardon and R. Rodriguez and Yu-Hui Rogers and Deanna L. Romblad and Bob Ruhfel and Richard Scott and Cynthia D. Sitter and M. Smallwood and E. Stewart and R. Strong and Ellen Suh and R. Thomas and Ni Ni Tint and Sukyee Tse and C. Vech and Gary Wang and Jeremy Wetter and S. Williams and M. Williams and Sandra M. Windsor and E. Winn-Deen and K. Wolfe and Jayshree Zaveri and Karena Zaveri and J. Abril and R. Guig{\'o} and M. Campbell and Kimmen V. Sjolander and Brian Karlak and A. Kejariwal and H. Mi and B. Lazareva and Thomas J. Hatton and A. Narechania and Karen Diemer and Anushya Muruganujan and N. Guo and S. Sato and V. Bafna and Sorin Istrail and R. Lippert and R. Schwartz and B. Walenz and S. Yooseph and D. Allen and A. Basu and J. Baxendale and Louis Blick and M. Caminha and John Carnes-Stine and Parris Caulk and Yen-Hui Chiang and My D. Coyne and C. Dahlke and A. D. Mays and M. Dombroski and Michael T. Donnelly and Dale Ely and Shiva Esparham and C. Fosler and H. Gire and S. Glanowski and K. Glasser and A. Głodek and M. Gorokhov and K. Graham and Barry Gropman and M. Harris and J. Heil and S. Henderson and J. Hoover and D. Jennings and C. Jordan and J. Jordan and John Kasha and L. Kagan and C. Kraft and A. Levitsky and M. Lewis and X. Liu and J. Lopez and Daniel S. Ma and William H. Majoros and J. McDaniel and S. Murphy and M. Newman and Dac-Trung Nguyen and N. Nguyen and Marc Nodell and Sue Pan and J. Peck and M. Peterson and W. Rowe and R. Sanders and J. Scott and M. Simpson and T. Smith and Arlan C. Sprague and Timothy B. Stockwell and R. Turner and E. Venter and M. Wang and M. Wen and D. Wu and Mitchell M. Wu and Ashley C. Xia and A. Zandieh and X. Zhu},
  pages={1304 - 1351}
  • J. Venter, M. Adams, +271 authors X. Zhu
  • Published 2001
  • Biology
  • Science
  • A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage of the genome) from both ends of plasmid clones made from the DNA of five individuals. Two assembly strategies—a whole-genome assembly and a regional chromosome assembly—were used, each combining sequence data from… CONTINUE READING
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