Corpus ID: 53701060

The Secondary Metabolites and Biosynthetic Gene Clusters of Marine Cyanobacteria . Applications in Biotechnology

@inproceedings{Ramaswamy2005TheSM,
  title={The Secondary Metabolites and Biosynthetic Gene Clusters of Marine Cyanobacteria . Applications in Biotechnology},
  author={Aishwarya V Ramaswamy and P. Flatt and Daniel and J. Edwards and T. L. Simmons and Bingnan Han and W. Gerwick},
  year={2005}
}
*For correspondence email bill.gerwick@oregonstate.edu Abstract Marine cyanobacteria have proven to be one of the most versatile marine producers of secondary metabolites. Many of these metabolites demonstrate antiproliferative activity (e.g. curacin A, dolastatins), acute cytotoxic activity (e.g. apratoxin, hectochlorin) or have specific neurotoxic activity (e.g. kalkitoxin, antillatoxin), making them invaluable as potential therapeutic leads or pharmacological tools. The predominant… Expand
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References

SHOWING 1-10 OF 189 REFERENCES
Nitrogen-containing metabolites from marine cyanobacteria.
  • 121
Phylogenetic evidence for the early evolution of microcystin synthesis.
  • A. Rantala, D. Fewer, +4 authors K. Sivonen
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2004
  • 455
  • PDF
Drugs from the seas – current status and microbiological implications
  • 540
Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites
  • S. O̅mura, H. Ikeda, +11 authors M. Hattori
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
  • 718
  • PDF
A genomics-guided approach for discovering and expressing cryptic metabolic pathways
  • 276
  • PDF
...
1
2
3
4
5
...