The Secondary Immune Response to a Hapten in Vitro

@article{Klinman1971TheSI,
  title={The Secondary Immune Response to a Hapten in Vitro},
  author={Norman R. Klinman},
  journal={The Journal of Experimental Medicine},
  year={1971},
  volume={133},
  pages={963 - 972}
}
The in vitro secondary stimulation of the production of anti-hapten antibody has been analyzed with a view to elucidating the role of the carrier molecule and cell-to-cell interactions in this response. Stimulation was carried out on fragment cultures of the spleens of irradiated BALB/c mice which had been reconstituted with 3-4 x 10(7) spleen cells from… CONTINUE READING